Scientists have spent a lot of effort trying to create cannabinoids with medical properties but no 'high.' New research suggests that there is already a solution, and it of the purest therapeutic kind. The cannabinoid that could erase decades of work is beta-caryophyllene (BCP). BCP is found in the essential oils of a variety of plants, including rosemary, hops, cloves, black pepper, & highly in copaiba.
While BCP was first synthesized in 1964, it wasn’t until 2008 that a group of German and Swiss scientists, led by Andreas Zimmer, PhD and Ildiko Racz, PhD of the University of Bonn, discovered that BCP is a cannabinoid.
And not just any cannabinoid, but one that acts specifically on the body’s CB2 cannabinoid pathways. On the other hand, the pathways responsible for the marijuana high, CB1 receptors, aren’t affected by BCP. Writing in the journal Proceedings of the National Academy of Sciences (PNAS), they summarized:
“Here, we report that the widespread plant volatile β-caryophyllene (BCP) selectively binds to the CB2 receptor and that it is a functional CB2 agonist. Intriguingly, BCP is a common constituent of the essential oils of numerous spice and food plants and a major component in Cannabis.”
Interestingly, scientists have been trying to develop a viable synthetic cannabinoid that targets only CB2 receptors for a very long time.
Many now exist, and research has shown the promise of CB2-selective cannabinoids in combating many inflammatory disorders, ranging from arthritis and bladder cystitis to multiple sclerosis and HIV-associated dementia. And all without the marijuana high.
But Dr. Racz and Dr. Zimmer’s latest study, published in the journal European Neuropsychopharmacology, shows that BCP produces similar anti-inflammatory effects. Although the study was only done in mice, they found that BCP given orally was more effective than injections of the synthetic CB2 cannabinoid JWH-133.
This, they note, suggests that BCP could indeed be a superior medicine than synthetics. Not to mention, it’s widely available as a food.
“It is likely that BCP belongs to a group of common plant natural products with major potential impact on human health. The oral intake of this dietary cannabinoid with vegetable food could be advantageous in the daily routine clinical practice over synthetic cannabinoid agonists.”
Comparing CBD oil and Copaiba - the compound that makes cannabis therapeutic is the beta-caryophyllene and its level in CBD is 35% and in Copaiba is 55%.
That makes Copaiba essential oil one of the most powerful natural substances to support your body in pain management, inflammation, among many other issues that cannabis is traditionally known to support.
And it is legal in all 50 states.
Plus it is offered in the Young Living starter kit at no additional cost.
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A lengthy, but very interesting NIH report Copaiba Oil-Resin Treatment Is Neuroprotective and Reduces Neutrophil Recruitment and Microglia Activation after Motor Cortex Excitotoxic Injury